Dr. Chang attended Johns Hopkins University for his B.A. in molecular biology prior to entering Georgetown University School of Medicine for his M.D. He then completed his pediatric residency at Children Hospital National Medical Center and his pediatric cardiology fellowship at Children Hospital of Philadelphia.
He accepted a position as attending cardiologist in the cardiovascular intensive care unit of Boston Children Hospital and as assistant professor at Harvard Medical School. He has been the medical director of several pediatric cardiac intensive care programs (including Children Hospital of Los Angeles and Texas Children Hospital) and is currently the medical director of the heart institute at Children Hospital of Orange County. He is a committee member of the National Institute of Health pediatric grant review committee. He is also known for several innovations in pediatric cardiac care, including introducing the cardiac drug milrinone and co-designing (with Dr. Michael DeBakey) the axial-type ventricular assist device in children.
He is the editor of several textbooks in pediatric cardiology, including Pediatric Cardiac Intensive Care and Heart Failure in Children and Young Adults. He is the founder of the Pediatric Cardiac Intensive Care Society (PCICS) that launched the multi-disciplinary focus on cardiac intensive care for children. He is also the founder of Asia-Pacific Pediatric Cardiac Society (APPCS), which united pediatric cardiologists and cardiac surgeons from 24 Asian countries and launched a biennial meeting in Asia that draws close to 1,000 attendees. This society will also be organizing medical missions to needy parts of Asia for advanced cardiac care in children and will be forming the Asia-Pacific Pediatric Cardiac Foundation, the charitable arm of the APPCS.
He has completed a Masters in Business Administration (MBA) in Health Care Administration at the University of Miami School of Business and graduated with the McCaw Award of Academic Excellence. He also completed a Masters in Public Health (MPH) in Health Care Policy at the Jonathan Fielding School of Public Health of the University of California, Los Angeles and graduated with the Dean Award for Academic Excellence. He is currently pursuing a Masters of Science in Biomedical Informatics with a sub-specialization in Artificial Intelligence at Stanford School of Medicine.
He is the founder and medical director of the nascent Medical Intelligence and Innovation Institute (MI3) that is supported by the Sharon Disney Lund Foundation. The institute is dedicated to implement data science and artificial intelligence in medicine and is the first institute of its kind in a hospital. The new institute is concomitantly dedicated to facilitate innovation in children health care all over the world. He is the organizing chair for the biennial Pediatrics2040: Emerging Trends and Future Innovations meeting as well as the director of the Medical Intelligence and Innovation Summer Internship Program, which mentors about 10-20 young physicians-to-be every summer.
He aims to build a physician-computer scientist interface to enhance all aspects of data science and artificial intelligence in health and medicine. He currently lectures widely on big data and artificial intelligence in medicine. He has also published review papers on big data and predictive analytics as well as machine learning and artificial intelligence in medicine. He is currently organizing a book project, Medical Intelligence: Big Data, Predictive Analytics, Machine Learning and Artificial Intelligence in Medicine.